Cannabinoid system of the lateral septum in the modulation of anxiety-like behaviors in rats

Cannabinoid system of the lateral septum in the modulation of anxiety-like behaviors in rats.

A large body of evidence suggests that the cannabinoid CB1 receptor plays a key role in the regulation of emotional behaviors.

The present study was designed to evaluate the effects of CB1 agonist and antagonist on anxiety-like behaviors in the lateral septum (LS) region of the rat brain using elevated plus maze test…

The results suggest that the cannabinoid system of the lateral septum modulates anxiety-like behavior through CB1 receptor.

(Hajizadeh Moghaddam A, Bigdellu R, Fatemi Tabatabaei SR, Roohbakhsh A. Cannabinoid System of the Lateral Septum in the Modulation of Anxiety-like Behaviors in Rats. Arch Iran Med. 2013; 16(12): 711 – 716.)

http://www.ams.ac.ir/AIM/NEWPUB/13/16/12/006.pdf


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